VLN Clinical Trials

The following are links to ongoing clinical trials in the recruiting phase for VLN Cigarettes, along with their locations.


Measuring Neuroadaptations in Response to Very Low Nicotine Content Cigarettes
ClinicalTrials.gov Identifier: NCT03612960

  • Penn State Health, Hershey, Pennsylvania, United States

Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace
ClinicalTrials.gov Identifier: NCT03272685

  • Tobacco Research Center, San Francisco, California, United States
  • Tobacco Research Programs, Minneapolis, Minnesota, United States
  • Tobacco, Durham, North Carolina, United States
  • Wake Forest Tobacco Control Center of Excellence, Winston-Salem, North Carolina, United States
  • Center for Interdisciplinary Research on Nicotine Addiction, Philadelphia, Pennsylvania, United States
  • Brown University Center for Alcohol and Addiction Studies School of Public Health, Providence, Rhode Island, United States

Very Low Nicotine Content Cigarettes and E-Cigarettes in Promoting Smoking Cessation in Daily and Intermittent Cigarette Smokers
ClinicalTrials.gov Identifier: NCT02964182

  • M D Anderson Cancer Center, Houston, Texas, United States

Cigarette Smoking Among Young Adults
ClinicalTrials.gov Identifier: NCT04340947

  • Health Promotion Research Center, Oklahoma City, Oklahoma, United States

Project 4, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Pregnant Women
ClinicalTrials.gov Identifier: NCT04033237

  • University of Kentucky, Lexington, Kentucky, United States
  • University of Vermont, Burlington, Vermont, United States

Evaluating New Nicotine Standards for Cigarettes – Project 3
ClinicalTrials.gov Identifier: NCT03194256

  • Brown University School of Public Health, Providence, Rhode Island, United States

Low Nicotine Cigarettes Plus Electronic Cigarettes
ClinicalTrials.gov Identifier: NCT04058717

  • Penn State College of Medicine, Hershey, Pennsylvania, United States

Young Adults and Low Nicotine Cigarettes
ClinicalTrials.gov Identifier: NCT03699865

  • Center for Interdisciplinary Research on Nicotine Addiction, University of Pennsylvania, Philadelphia, Pennsylvania, United States

Can Exposure to Brief Messages Correct Misperceptions
ClinicalTrials.gov Identifier: NCT05129592

  • Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States

Reduced Nicotine Cigarette Purchasing Decisions
ClinicalTrials.gov Identifier: NCT04999644

  • Behavioral Pharmacology Research Unit, Baltimore, Maryland, United States

Nicotine Differences in Smokers
ClinicalTrials.gov Identifier: NCT05159934

  • Veterans Affairs Hospital, West Haven, Connecticut, United States

Smoking and Ventricular Repolarization
ClinicalTrials.gov Identifier: NCT03916341

  • U California, Los Angeles, California, United States

Electronic Cigarettes as a Harm Reduction Strategy in Individuals With Substance Use Disorder
ClinicalTrials.gov Identifier: NCT04063267

  • NYU Langone Health, New York, New York, United States

Young Adults’ Reactions to Low Nicotine Cigarette Advertising
ClinicalTrials.gov Identifier: NCT04906148

  • Center for Interdisciplinary Research on Nicotine Addiction, University of Pennsylvania, Philadelphia, Pennsylvania, United States

Metabolism of NNK in Japanese Americans
ClinicalTrials.gov Identifier: NCT04228952

  • University of Hawaii Cancer Center, Honolulu, Hawaii, United States